Why We Use Nano-Hydroxyapatite in Our Toothpaste
At NOBIESSE™, we believe oral care should do more than just clean—it should actively support the health and strength of your smile. That’s why we use nano-hydroxyapatite (nHA), a breakthrough, biocompatible ingredient clinically shown to remineralize enamel, reduce sensitivity, and promote long-term oral health—naturally.

Why Switch to Nano-Hydroxyapatite Toothpaste?
Making the switch from conventional fluoride toothpaste to NOBIESSE™ with nano-hydroxyapatite offers a wide range of benefits:
- Strengthens Enamel Naturally
Rebuilds and reinforces enamel without the risks associated with fluoride. - Reduces Tooth Sensitivity
Fills in exposed dentin and helps block nerve pathways to ease discomfort. - Whitens Gently
Lifts surface stains without harsh abrasives or synthetic whiteners. - Supports the Oral Microbiome
Gently detoxifies and helps maintain a healthy balance of bacteria in the mouth. - No Synthetic Aftertaste or Foaming Agents
Free from SLS, fluoride, artificial flavors, and harsh chemicals.
Featured in Both NOBIESSE™ Toothpastes:
Fluoride-Free Whitening Toothpaste
A clinically inspired formula with gentle brightening agents like charcoal and hydrogen peroxide, paired with peppermint and clove essential oils for a truly fresh finish.
Key Ingredients:
Nano-Hydroxyapatite, Charcoal, Hydrogen Peroxide, Dead Sea Salt, Diatomaceous Earth, Peppermint + Clove Essential Oils
Original Fluoride-Free Toothpaste
A balanced, everyday formula that strengthens, detoxifies, and supports a thriving oral microbiome—perfect for long-term use without irritation.
Key Ingredients:
Nano-Hydroxyapatite, Dead Sea Salt, Bentonite Clay, Coconut Oil, Peppermint + Clove Essential Oils


The NOBIESSE™ Difference
Made in the USA
Family-Owned, Small Batch Production
Clinically Proven, Non-Toxic Ingredients
Safe for All Ages
Give your smile the upgrade it deserves—with science-backed support that’s safe, clean, and crafted with care.
What is nano-hydroxyapatite?
Nano-hydroxyapatite (nHA) is a form of calcium phosphate—the same mineral your teeth and bones are made of. In toothpaste, these nano-sized particles help fill in microscopic cracks and areas of enamel loss, reinforcing your teeth at a structural level.
What makes nano-hydroxyapatite different from fluoride?
Nano-hydroxyapatite works by physically filling in and rebuilding weakened enamel, mimicking the natural structure of your teeth. Unlike fluoride, which hardens enamel through a chemical reaction, nHA is biocompatible and works at a structural level—without the risks of fluorosis or overexposure.
Is nano-hydroxyapatite safe for kids and pregnant women?
Yes. Nano-hydroxyapatite is considered non-toxic and safe for all ages, including children and those who are pregnant or breastfeeding. It’s a preferred alternative for families who want effective remineralization without fluoride.
Does nano-hydroxyapatite really help with tooth sensitivity?
Absolutely. nHA particles penetrate the small tubules in your dentin (the layer beneath your enamel), helping to block nerve exposure and reduce the discomfort associated with hot, cold, or sweet foods.
How long does it take to see results from using nHA toothpaste?
Most users begin noticing a reduction in sensitivity and a cleaner, smoother feel within 1–2 weeks of daily use. Long-term benefits like enamel strengthening and stain reduction improve over time with consistent brushing.